Dementia Research Today is a free monthly online journal that collates and summarizes the latest research about Dementia, including details on symptoms, alzheimers, senile dementia, causes.

Volume 7 (2010), Issue 4 (April)

1. Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington's disease.
   J Neurosci, 30(13): 4552-61. [Abstract] [Full-text]
2. Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases.
   J Neurosci, 30(13): 4528-35. [Abstract] [Full-text]
3. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
   Proc Natl Acad Sci U S A, 107(13): 6058-63. [Abstract] [Full-text]
4. Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's.
   Proc Natl Acad Sci U S A, 107(13): 5949-54. [Abstract] [Full-text]
5. HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications.
   J Leukoc Biol, 87(4): 621-6. [Abstract] [Full-text]
6. RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.
   FASEB J, 24(4): 1043-55. [Abstract] [Full-text]
7. Survival in progressive supranuclear palsy and frontotemporal dementia.
   J Neurol Neurosurg Psychiatry, 81(4): 441-5. [Abstract] [Full-text]
8. A case with Hodgkin lymphoma and fronto-temporal lobular degeneration (FTLD)-like dementia facilitated by chemotherapy.
   Jpn J Clin Oncol, 40(4): 365-8. [Abstract] [Full-text]
9. Metabolic syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Ageing.
   J Neurol Neurosurg Psychiatry, 81(4): 433-40. [Abstract] [Full-text]
10. Progression in prediagnostic Huntington disease.
    J Neurol Neurosurg Psychiatry, 81(4): 379-84. [Abstract] [Full-text]
11. Design and development of non-fibrillar amyloid beta as a potential Alzheimer vaccine.
    Biochem Biophys Res Commun, 394(2): 393-7. [Abstract] [Full-text]
12. Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment.
    Arch Gen Psychiatry, 67(4): 414-22. [Abstract] [Full-text]
13. A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.
    J Neurosci, 30(14): 4845-56. [Abstract] [Full-text]
14. Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome.
    Proc Natl Acad Sci U S A, 107(14): 6538-43. [Abstract] [Full-text]
15. Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease.
    Proc Natl Acad Sci U S A, 107(14): 6498-503. [Abstract] [Full-text]
16. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline.
    Brain, 133: 1163-72. [Abstract] [Full-text]
17. Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.
    Brain, 133: 1143-54. [Abstract] [Full-text]
18. Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease.
    Brain, 133: 1094-110. [Abstract] [Full-text]
19. HMGA1a trapping of U1 snRNP at an authentic 5' splice site induces aberrant exon skipping in sporadic Alzheimer's disease.
    Mol Cell Biol, 30(9): 2220-8. [Abstract] [Full-text]
20. Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study.
    Brain, 133: 1155-62. [Abstract] [Full-text]
21. The cognitive organization of music knowledge: a clinical analysis.
    Brain, 133: 1200-13. [Abstract] [Full-text]
22. Midregional Proenkephalin A and N-terminal Protachykinin A are decreased in the cerebrospinal fluid of patients with dementia disorders and acute neuroinflammation.
    J Neuroimmunol, 221(1): 62-7. [Abstract] [Full-text]
23. Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study.
    Neurology, 74(15): 1208-16. [Abstract] [Full-text]
24. Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.
    Biochemistry, 49(15): 3261-72. [Abstract] [Full-text]
25. Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes.
    Proc Natl Acad Sci U S A, 107(15): 7036-41. [Abstract] [Full-text]
26. Relationship between low levels of high-density lipoprotein cholesterol and dementia in the elderly. The InChianti study.
    J Gerontol A Biol Sci Med Sci, 65(5): 559-64. [Abstract] [Full-text]
27. High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease.
    Oncogene, 29(15): 2165-71. [Abstract] [Full-text]
28. Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.
    J Neurochem, 113(2): 389-401. [Abstract] [Full-text]
29. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
    J Neurochem, 113(1): 248-61. [Abstract] [Full-text]
30. Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons.
    J Neurochem, 113(3): 761-71. [Abstract] [Full-text]
31. Using the life course perspective to study the entry into the illness trajectory: the perspective of caregivers of people with Alzheimer's disease.
    Soc Sci Med, 70(10): 1501-8. [Abstract] [Full-text]
32. Neuronal nicotinic acetylcholine receptor-cholesterol crosstalk in Alzheimer's disease.
    FEBS Lett, 584(9): 1856-63. [Abstract] [Full-text]
33. Calcium signaling and amyloid toxicity in Alzheimer disease.
    J Biol Chem, 285(17): 12463-8. [Abstract] [Full-text]
34. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.
    J Biol Chem, 285(17): 13107-20. [Abstract] [Full-text]
35. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease.
    Mol Pharmacol, 77(5): 715-23. [Abstract] [Full-text]
36. Effect of Alzheimer disease genetic risk disclosure on dietary supplement use.
    Am J Clin Nutr, 91(5): 1402-7. [Abstract] [Full-text]
37. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease.
    Brain, 133: 1352-67. [Abstract] [Full-text]
38. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.
    Brain, 133: 1328-41. [Abstract] [Full-text]
39. Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.
    Brain, 133: 1342-51. [Abstract] [Full-text]
40. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology.
    Brain, 133: 1312-27. [Abstract] [Full-text]
41. "Easing the way" for spouse caregivers of individuals with dementia: a pilot feasibility study of a grief intervention.
    Res Gerontol Nurs, 3(2): 89-99. [Abstract] [Full-text]
42. One-step multiplex polymerase chain reaction for preimplantation genetic diagnosis of Huntington disease.
    Fertil Steril, 93(7): 2411-2. [Abstract] [Full-text]
43. Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
    Nat Neurosci, 13(5): 567-76. [Abstract] [Full-text]
44. The older adult driver with cognitive impairment: "It's a very frustrating life".
    JAMA, 303(16): 1632-41. [Abstract] [Full-text]
45. Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
    Proc Natl Acad Sci U S A, 107(17): 7969-74. [Abstract] [Full-text]
46. SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.
    Proc Natl Acad Sci U S A, 107(17): 7927-32. [Abstract] [Full-text]
47. Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.
    J Neurosci, 30(17): 6132-42. [Abstract] [Full-text]
48. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
    J Neurosci, 30(17): 5948-57. [Abstract] [Full-text]
49. Alzheimer's disease: strategies for disease modification.
    Nat Rev Drug Discov, 9(5): 387-98. [Abstract] [Full-text]
50. Inverse relationship between cerebrovascular lesions and severity of lewy body pathology in patients with lewy body diseases.
    J Neuropathol Exp Neurol, 69(5): 442-8. [Abstract] [Full-text]
51. Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations.
    J Neuropathol Exp Neurol, 69(5): 449-54. [Abstract] [Full-text]
52. Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils.
    FASEB J, 24(5): 1311-9. [Abstract] [Full-text]
53. Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis.
    FASEB J, 24(5): 1431-41. [Abstract] [Full-text]
54. Regional metabolic alteration of Alzheimer's disease in mouse brain expressing mutant human APP-PS1 by 1H HR-MAS.
    Behav Brain Res, 211(1): 125-31. [Abstract] [Full-text]

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